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Multicentric infections were documented in 12.3% (25/200) of cases. Nearly 50% of koalas had 1 to 3 concurrent respiratory lesions, and over half had more than one concurrent cardiac lesion. Cardiac lesions were commonly due to Nocardia spp. (44.0%) and Mycobacterium spp. (30.0%) and uncommonly due to Salmonella spp. and Streptococcus spp. A single case had a pulmonary abscess caused by Candida spp. and another koala had a solitary Pasteurella spp. pneumonia. The unexpected finding of Salmonella spp. in a koala raises questions about the potential for the organism to be capable of causing disease in koalas, which are typically Salmonella-free37. One koala presented with Salmonella spp. pneumonia, a concurrent traumatic injury to the left udder, suggestive of a contiguous infection. Interestingly, a recent survey of koala health in Western Australia found Salmonella enterica* subsp*. enterica* serovar O1,5:g,z41,43 to be the most common isolate in healthy koalas and a cause of systemic and intestinal infection in some koalas43. Different species of Salmonella have been documented to cause disease in koalas44,45,46, and there have been previous reports of disease in koalas associated with other species of Salmonella47,48. Koalas are considered to be resistant to a broad range of intracellular pathogens, however, co-occurring infectious disease may significantly impact koala health and survival. The koala population is also experiencing a significant threat of disease due to the emergence of multidrug-resistant (MDR) Salmonella enterica* subsp*. enterica* serovar Paratyphi B48 which is associated with koala mortality29. While there have been no confirmed cases of Salmonella enterica* subsp*.
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